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JACC Journals podcasts deliver expert insights and key takeaways from the latest cardiovascular science. Hosted by Editor-in-Chief Harlan M. Krumholz, MD, SM, JACC This Week offers engaging summaries and commentary from each weekly issue, complemented by a growing library of deep-dive interviews, global perspectives, and author conversations that highlight the research and innovation shaping cardiovascular medicine worldwide.

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  2. Amyloidosis in Focus: Biomarkers, Structural Insights & Therapeutic Strategy | JACC This Week

Amyloidosis in Focus: Biomarkers, Structural Insights & Therapeutic Strategy | JACC This Week

Aug 4, 2025

In this mini focus issue of JACC This Week, Editor-in-Chief Dr. Harlan Krumholz explores the evolving landscape of cardiac amyloidosis care. From structural and biomarker findings in the HELIOS-B substudy to broader discussions on access, treatment sequencing, and multidisciplinary care, this episode highlights new momentum in ATTR-CM management.
Also covered: a sham-controlled trial on compression therapy for vasovagal syncope and pooled trial data on DOAC use in frail older adults with atrial fibrillation. Fast-moving insights, practical takeaways, and a clear message—amyloidosis is no longer rare and mysterious, but a condition we can monitor, modify, and manage.