Preview Mode Links will not work in preview mode

Developed for busy clinicians, JACC Journals podcasts provide key insights into top cardiovascular science published in the JACC family of Journals. The JACC Podcast features article summaries recorded by Valentin Fuster, MD, PhD, MACC, from each weekly issue of JACC. 

  1. All Episodes
  2. Revisiting the SUMMIT Trial | JACC Deep Dive

Revisiting the SUMMIT Trial | JACC Deep Dive

May 6, 2025

This JACC Deep Dive in our May 13 issue highlights new findings from the SUMMIT CKD study, showing that terzepatide improves symptoms, function, and weight in patients with HFpEF and obesity—regardless of kidney function. The analysis also underscores the importance of using both creatinine and cystatin C to better assess kidney health. Reviewers praised the study’s methodological rigor and dual focus, while noting the need for larger, long-term trials to confirm renal outcomes.