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JACC Journals podcasts deliver expert insights and key takeaways from the latest cardiovascular science. Hosted by Editor-in-Chief Harlan M. Krumholz, MD, SM, JACC This Week offers engaging summaries and commentary from each weekly issue, complemented by a growing library of deep-dive interviews, global perspectives, and author conversations that highlight the research and innovation shaping cardiovascular medicine worldwide.

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  2. Revisiting the SUMMIT Trial | JACC Deep Dive

Revisiting the SUMMIT Trial | JACC Deep Dive

May 6, 2025

This JACC Deep Dive in our May 13 issue highlights new findings from the SUMMIT CKD study, showing that terzepatide improves symptoms, function, and weight in patients with HFpEF and obesity—regardless of kidney function. The analysis also underscores the importance of using both creatinine and cystatin C to better assess kidney health. Reviewers praised the study’s methodological rigor and dual focus, while noting the need for larger, long-term trials to confirm renal outcomes.